PDF(Pubmed)
Abstract：
A 32-year-old woman with schizophrenia and persistent auditory verbal hallucinations (AVHs), which caused continuous suicidal thoughts and depression, was treated with electroconvulsive therapy (ECT) of an acute course followed by maintenance ECT (M-ECT) augmented onto clozapine for 7 years. Although the general psychopathology and AVHs initially reduced slightly with ECT and clozapine, her AVHs and suicidal thoughts did not decrease subjectively. When 3 years of M-ECT, her voices declined sharply, and improvement was maintained for 2 years thereafter. A total 91 ECT sessions were performed. The daily clozapine dose was decreased from 325 to 200 mg and plasma levels remained higher than 350 ng/ml; there were no noticeable cognitive side effects. In summary, we report a case showing a sudden sharp reduction in persistent AVHs after 3 years of long-term M-ECT.
摘要：
一名32岁的女性患有精神分裂症和持续性听觉言语幻觉（AVHs），导致持续的自杀念头和抑郁,接受急性电休克疗法（ECT）治疗，然后在氯氮平基础上增加维持ECT（M-ECT）治疗7年。虽然一般的精神病理学和AVHs最初使用ECT和氯氮平略有减少，她的AVHs和自杀念头主观上并未减少.当3年的M-ECT，她的声音急剧下降，并在此后2年内保持了改善。总共进行了91次ECT会话。每日氯氮平剂量从325mg降至200mg，血浆水平仍高于350ng/ml；没有明显的认知副作用。总之,我们报告了一例病例,显示长期M-ECT治疗3年后持续性AVHs突然急剧减少.
