Abstract：
Hypercoagulable disorders can compromise success of free flap reconstruction. Factor V Leiden is one such disorder for which only one previously reported case of successful free tissue transfer in the head and neck has been described. We report a 70-year-old woman with factor V Leiden treated for stage IVA squamous cell carcinoma of the mandible with a composite resection and reconstruction with an osteocutaneous scapular free tissue transfer. The free tissue transfer occurred without complications, in the setting of intraoperative heparin, postoperative aspirin, and enoxaparin. The free tissue transfer continues to be viable at her most recent follow-up appointment. The hypercoagulable patient represents a diverse presentation of increased coagulation risk in the perioperative period. Considering a patient\'s history and understanding available treatment adjuncts can factor heavily in a patient with factor V Leiden successfully undergoing free tissue transfer for head and neck defects.
摘要：
高凝性疾病会损害游离皮瓣重建的成功。因子VLeiden是一种这样的疾病，以前仅报道了一例成功进行头颈部游离组织转移的病例。我们报告了一名70岁的女性，患有V因子Leiden，对下颌骨IVA鳞状细胞癌进行了综合切除和重建，并进行了骨皮肩cap骨游离组织转移。游离组织转移无并发症发生，在术中肝素的设置中，术后阿司匹林,和依诺肝素.在她最近的随访预约中,游离的组织转移仍然是可行的。高凝患者在围手术期表现出多种凝血风险增加。考虑到患者的病史和对可用治疗辅助手段的了解，对于患有V因子的患者而言，莱顿成功进行了头颈部缺损的游离组织转移。
