关键词: cachexia exercise lifestyle intervention metastatic disease nutrition pancreatic cancer psychological support

来  源:   DOI:10.2144/fsoa-2020-0165   PDF(Pubmed)

Abstract:
Pancreatic cancer remains an aggressive disease, with a poor prognosis and a high risk of incurring into cachexia. Supportive care, such as exercise, nutritional and psychological support, may be effective in reducing functional loss, psychological distress and improving nutritional status. We report the effect of 12 weeks of multimodal lifestyle intervention in a 55-year-old female, diagnosed with unresectable body/tail pancreatic cancer and metastasis in the liver, bone, lymph node and lung, to counteract cachexia. The multimodal program resulted safe and feasible. Over 12 weeks, considerable improvements were found in body weight, health-related physical fitness, nutritional status, distress scores, anxiety and depression levels. These findings highlight the potential role of integrated supportive interventions to manage metastatic cancer and cancer-induced cachexia.
摘要:
胰腺癌仍然是一种侵袭性疾病,预后差,发生恶病质的风险很高。支持性护理,比如锻炼,营养和心理支持,可以有效减少功能损失,心理困扰和改善营养状况。我们报告了12周多模式生活方式干预对一名55岁女性的影响,诊断为不可切除的体/尾胰腺癌和肝脏转移,骨头,淋巴结和肺,来抵消恶病质.多模态方案安全可行。超过12周,体重有了相当大的改善,与健康相关的身体健康,营养状况,苦恼分数,焦虑和抑郁水平。这些发现强调了综合支持性干预措施在治疗转移性癌症和癌症引起的恶病质方面的潜在作用。
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