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Abstract：
UNASSIGNED: Statin eligibility based on the American College of Cardiology/American Heart Association cholesterol guidelines among patients with diabetes admitted with first time acute myocardial infarction has not been evaluated in the Middle East.
UNASSIGNED: To assess statin eligibility for diabetic patients admitted with first time myocardial infarction in Jordan according to ACC/AHA guidelines.
UNASSIGNED: Consecutive patients admitted with a first acute myocardial infarction who were not taking statins, and had their serum lipoproteins measured upon hospital admission were enrolled in the study. Statin eligibility among patients with diabetes admitted with first time myocardial infarction was determined based on the ACC/AHA guidelines.
UNASSIGNED: Of 774 patients enrolled, 292 (37.30%) had diabetes. Compared with non-diabetic patients, those with diabetes were females, older, more hypertension, more hypercholesterolemia, more triglycerides, more diastolic blood pressure, less smokers and less low density lipoprotein. Among patients with diabetes, 242 diabetic patients (82.9%) were statin eligible, including 20 (6.90%) for having high serum levels of low density lipoprotein cholesterol (LDL-C) >190 mg/dL, and 222 (76%) for being aged 40-75 years with LDL-C 70-189 mg/dL. No patient had a calculated atherosclerotic cardiovascular risk score ≥7.5%. On the other hand, 393 non-diabetic patients (81.3%) were statin eligible, including 41 (8.50%) for having high serum levels of low density lipoprotein cholesterol (LDL-C) >190 mg/dL, and 351 (72.80%) for being aged 40-75 years with LDL-C 70-189 mg/dL.
UNASSIGNED: Based on the ACC/AHA guidelines, the majority of patients with diabetes admitted with first acute myocardial infarction would have been eligible for statin treatment if they have LDL-c >190 mg/dl or aged 40-75 years old and they have their LDL 70-189 mg/gl. More efforts should be taken for patients who are female, older than 50 years, hypertensive, elevated diastolic blood pressure have hypercholesterolemia, and elevated triglycerides because of their significant association with diabetes.
UNASSIGNED: To assess statin eligibility for diabetic patients admitted with first time myocardial infarction in Jordan according to ACC/AHA guidelines.
UNASSIGNED: Consecutive patients admitted with a first acute myocardial infarction who were not taking statins, and had their serum lipoproteins measured upon hospital admission were enrolled in the study. Statin eligibility among patients with diabetes admitted with first time myocardial infarction was determined based on the ACC/AHA guidelines.
UNASSIGNED: Of 774 patients enrolled, 292 (37.30%) had diabetes. Compared with non-diabetic patients, those with diabetes were females, older, more hypertension, more hypercholesterolemia, more triglycerides, more diastolic blood pressure, less smokers and less low density lipoprotein. Among patients with diabetes, 242 diabetic patients (82.9%) were statin eligible, including 20 (6.90%) for having high serum levels of low density lipoprotein cholesterol (LDL-C) >190 mg/dL, and 222 (76%) for being aged 40-75 years with LDL-C 70-189 mg/dL. No patient had a calculated atherosclerotic cardiovascular risk score ≥7.5%. On the other hand, 393 non-diabetic patients (81.3%) were statin eligible, including 41 (8.50%) for having high serum levels of low density lipoprotein cholesterol (LDL-C) >190 mg/dL, and 351 (72.80%) for being aged 40-75 years with LDL-C 70-189 mg/dL.
UNASSIGNED: Based on the ACC/AHA guidelines, the majority of patients with diabetes admitted with first acute myocardial infarction would have been eligible for statin treatment if they have LDL-c >190 mg/dl or aged 40-75 years old and they have their LDL 70-189 mg/gl. More efforts should be taken for patients who are female, older than 50 years, hypertensive, elevated diastolic blood pressure have hypercholesterolemia, and elevated triglycerides because of their significant association with diabetes.
摘要：
■根据美国心脏病学会/美国心脏协会胆固醇指南，在中东尚未对首次急性心肌梗死的糖尿病患者中的他汀类药物资格进行评估。
■根据ACC/AHA指南，评估约旦首次心肌梗死的糖尿病患者的他汀类药物资格。
■连续入院的首次急性心肌梗死患者未服用他汀类药物，并在入院时测量其血清脂蛋白被纳入研究。根据ACC/AHA指南确定首次心肌梗死的糖尿病患者的他汀类药物资格。
■在774名患者中，292人（37.30%）患有糖尿病。与非糖尿病患者相比，糖尿病患者是女性，年长的,更多的高血压，更多的高胆固醇血症，更多的甘油三酯，更多的舒张压，吸烟者少，低密度脂蛋白少。在糖尿病患者中，242例糖尿病患者（82.9%）符合他汀类药物的要求，包括20（6.90％）具有高血清水平的低密度脂蛋白胆固醇（LDL-C）>190mg/dL，和222（76％）的年龄为40-75岁，LDL-C70-189mg/dL。没有患者的动脉粥样硬化心血管风险评分≥7.5%。另一方面,393例非糖尿病患者（81.3%）符合他汀类药物，包括41（8.50％）具有高血清水平的低密度脂蛋白胆固醇（LDL-C）>190mg/dL，和351（72.80％）为40-75岁，LDL-C70-189mg/dL。
■根据ACC/AHA指南，如果LDL-c>190mg/dl或年龄在40~75岁,且LDL为70~189mg/gl,则大多数首次急性心肌梗死的糖尿病患者符合他汀类药物治疗的条件.应该为女性患者付出更多努力，50岁以上，高血压，舒张压升高有高胆固醇血症，和甘油三酯升高，因为它们与糖尿病显著相关。
■根据ACC/AHA指南，评估约旦首次心肌梗死的糖尿病患者的他汀类药物资格。
■连续入院的首次急性心肌梗死患者未服用他汀类药物，并在入院时测量其血清脂蛋白被纳入研究。根据ACC/AHA指南确定首次心肌梗死的糖尿病患者的他汀类药物资格。
■在774名患者中，292人（37.30%）患有糖尿病。与非糖尿病患者相比，糖尿病患者是女性，年长的,更多的高血压，更多的高胆固醇血症，更多的甘油三酯，更多的舒张压，吸烟者少，低密度脂蛋白少。在糖尿病患者中，242例糖尿病患者（82.9%）符合他汀类药物的要求，包括20（6.90％）具有高血清水平的低密度脂蛋白胆固醇（LDL-C）>190mg/dL，和222（76％）的年龄为40-75岁，LDL-C70-189mg/dL。没有患者的动脉粥样硬化心血管风险评分≥7.5%。另一方面,393例非糖尿病患者（81.3%）符合他汀类药物，包括41（8.50％）具有高血清水平的低密度脂蛋白胆固醇（LDL-C）>190mg/dL，和351（72.80％）为40-75岁，LDL-C70-189mg/dL。
■根据ACC/AHA指南，如果LDL-c>190mg/dl或年龄在40~75岁,且LDL为70~189mg/gl,则大多数首次急性心肌梗死的糖尿病患者符合他汀类药物治疗的条件.应该为女性患者付出更多努力，50岁以上，高血压，舒张压升高有高胆固醇血症，和甘油三酯升高，因为它们与糖尿病显著相关。
