关键词: Clinical symptom Cytochrome oxidase I Dirofilaria repens Eye Filarial Human Microfilaria Ocular infection

Mesh : Animals Cyclooxygenase 1 / genetics Czech Republic Dirofilaria repens / cytology genetics isolation & purification Dirofilariasis / parasitology pathology Eye Infections, Parasitic / parasitology pathology Female Helminth Proteins / genetics Humans Microfilariae / isolation & purification Middle Aged

来  源:   DOI:10.1007/s00436-020-07003-9

Abstract:
Dirofilaria repens and Dirofilaria immitis are the most common filarial species affecting humans in Europe. Dirofilaria repens causes subcutaneous or ocular infection, whereas D. immitis is responsible mainly for the pulmonary form. In this report, we present the first human case of periorbital dirofilariasis in the Czech Republic. A 58-year-old woman suffered from an eyelid oedema, redness and pain in the left eye. After excising the parasite from her eyelid, all clinical symptoms disappeared. Based on the morphology and cytochrome oxidase I sequencing, the parasite was identified as D. repens. Histology revealed that the excised worm was female with absent microfilariae in uteri. With respect to the length of the incubation period and the sequence identity with a known Czech isolate, we concluded that D. repens was most likely of autochthonous origin.
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