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Abstract：
Pseudoangiomatous stromal hyperplasia (PASH), a rare, noncancerous lesion, is often an incidental finding on magnetic resonance imaging (MRI)-guided biopsy analysis of other breast lesions. We sought to describe the characteristics of PASH on MRI and identify the extent to which these characteristics are correlated with the amount of PASH in the pathology specimens. We identified 69 patients who underwent MRI-guided biopsies yielding a final pathological diagnosis of PASH between 2008 and 2015. We analyzed pre-biopsy MRI scans to document the appearance of the lesions of interest. All biopsy samples were classified as having ≤50% PASH or ≥51% PASH present on the pathological specimen. On MRI, 9 lesions (13%) appeared as foci, 19 (28%) appeared as masses with either washout or persistent kinetics, and 41 (59%) appeared as regions of nonmass enhancement. Of this latter group, 33 lesions (80%) showed persistent kinetic features. Masses, foci, and regions of nonmass enhancement did not significantly correlate with the percentage of PASH present in the biopsy specimens (P ≥ .05). Our findings suggest that PASH has a wide-ranging appearance on MRI but most commonly appears as a region of nonmass enhancement with persistent kinetic features. Our finding that most specimens had ≤50% PASH supports the notion that PASH is usually an incidental finding. We did not identify a definitive imaging characteristic that reliably identifies PASH.
摘要：
假血管瘤间质增生(PASH),一种罕见的，非癌性病变，通常是磁共振成像（MRI）引导的其他乳腺病变活检分析的偶然发现。我们试图描述MRI上的PASH特征，并确定这些特征与病理标本中PASH含量相关的程度。我们确定了69例接受MRI引导活检的患者，这些患者在2008年至2015年间最终病理诊断为PASH。我们分析了活检前的MRI扫描，以记录感兴趣的病变的外观。所有活检样本均被分类为病理样本上存在≤50%PASH或≥51%PASH。核磁共振成像,9个病灶（13%）出现病灶，19(28%)出现为具有冲洗或持续动力学的质量，41（59％）出现非质量增强区域。在后一组中，33个病变（80％）显示出持续的动力学特征。群众,焦点,非肿块增强区域与活检标本中存在的PASH百分比无显著相关性(P≥.05).我们的发现表明，PASH在MRI上具有广泛的外观，但最常见的表现为具有持续动力学特征的非质量增强区域。我们发现大多数标本的PASH≤50％，这支持了PASH通常是偶然发现的观点。我们没有确定可靠地识别PASH的明确成像特征。
