关键词: antimicrobial therapy intraabdominal infection nutrition source control treatment failure

Mesh : China Critical Care Fistula Humans Intraabdominal Infections / diagnosis drug therapy Surgeons

来  源:   DOI:10.1093/cid/ciaa1513   PDF(Sci-hub)

Abstract:
The Chinese guidelines for IAI presented here were developed by a panel that included experts from the fields of surgery, critical care, microbiology, infection control, pharmacology, and evidence-based medicine. All questions were structured in population, intervention, comparison, and outcomes format, and evidence profiles were generated. Recommendations were generated following the principles of the Grading of Recommendations Assessment, Development, and Evaluation system or Best Practice Statement (BPS), when applicable. The final guidelines include 45 graded recommendations and 17 BPSs, including the classification of disease severity, diagnosis, source control, antimicrobial therapy, microbiologic evaluation, nutritional therapy, other supportive therapies, diagnosis and management of specific IAIs, and recognition and management of source control failure. Recommendations on fluid resuscitation and organ support therapy could not be formulated and thus were not included. Accordingly, additional high-quality clinical studies should be performed in the future to address the clinicians\' concerns.
摘要:
这里介绍的中国IAI指南是由一个小组制定的,其中包括来自外科领域的专家,重症监护,微生物学,感染控制,药理学,和循证医学。所有问题都是以人口为单位的,干预,比较,和结果格式,并生成了证据资料。建议是根据建议分级评估的原则生成的,发展,和评估系统或最佳实践声明(BPS),适用时。最终指南包括45个分级建议和17个BPS,包括疾病严重程度的分类,诊断,源代码控制,抗菌治疗,微生物学评价,营养治疗,其他支持疗法,特定IAIs的诊断和管理,以及源头控制失效的识别和管理。无法制定有关液体复苏和器官支持治疗的建议,因此未包括在内。因此,未来应开展更多高质量的临床研究,以解决临床医生的担忧.
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