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Abstract：
Talaromyces marneffei causes fatal invasive mycosis in Southeast Asia. Diagnosis by culture has limited sensitivity and can result in treatment delay. We describe the use of a novel Mp1p enzyme immunoassay (EIA) to identify blood culture-negative talaromycosis, subsequently confirmed by bone marrow cultures. This EIA has the potential to speed diagnosis, enabling early therapy initiation.
摘要：
马尔尼菲塔拉酵母在东南亚引起致命的侵袭性真菌病。通过培养的诊断具有有限的灵敏度并且可导致治疗延迟。我们描述了使用一种新型的Mp1p酶免疫测定法（EIA）来鉴定血培养阴性的塔拉真菌病，随后通过骨髓培养证实。这个EIA有可能加速诊断，使早期开始治疗。
