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Abstract：
Executive function (EF) may predict sexual risk-taking and HIV risk in young women in rural South Africa. We tested associations between EF and seven risky behavioural outcomes: binge drinking, illicit substance use, unprotected vaginal sex, concurrent sexual relationships, transactional sex, herpes simplex virus type 2 (HSV-2) infection, and HIV infection. We compared EF in young women with HIV to matched controls. 1080 young women underwent cognitive assessments. Better verbal short-term memory was associated with a lower risk of HSV-2 (OR 0.77; 95% CI 0.69, 0.86; p < 0.001). Uncorrected trends (p < 0.05) were better verbal working memory being associated with a lower risk of concurrency, better planning with a lower risk of illicit drug use, and better affective inhibition with a lower risk of transactional sex. 78 participants with sexually acquired HIV were matched with 153 HIV-negative controls and had poorer verbal working memory than controls (Hedge\'s g = -0.38; 95% CI -0.66, -0.10; p = 0.0076), but this was non-significant after adjustment. EF\'s contribution to young women\'s risky behaviour in this context does not hold when stringent statistical corrections are applied, with only verbal short term memory reaching statistical significance as predictor. Replication in other samples is recommended.
摘要：
执行功能（EF）可以预测南非农村年轻女性的性风险和艾滋病毒风险。我们测试了EF和七个危险行为结果之间的关联：暴饮暴食，非法药物使用,无保护的阴道性行为,同时发生的性关系,交易性，单纯疱疹病毒2型（HSV-2）感染，和艾滋病毒感染。我们将感染艾滋病毒的年轻女性的EF与匹配的对照组进行了比较。1080名年轻女性接受了认知评估。较好的言语短期记忆与较低的HSV-2风险相关(OR0.77;95%CI0.69,0.86;p<0.001)。未校正的趋势（p<0.05）是更好的口头工作记忆与较低的并发风险相关，更好的规划，降低非法药物使用的风险，和更好的情感抑制，交易性行为的风险较低。78名性获得性HIV的参与者与153名HIV阴性对照者相匹配，其口头工作记忆比对照者差(Hedge\sg=-0.38;95%CI-0.66,-0.10;p=0.0076)，但调整后这并不重要。在这种情况下，英孚对年轻女性的危险行为的贡献在应用严格的统计校正时不成立，只有言语短时记忆达到统计意义作为预测因子。建议在其他样品中复制。
