关键词: SerpinB9 antitumor immune response cancer-associated fibroblasts granzyme B
Mesh : Animals Apoptosis / drug effects Breast Neoplasms / immunology pathology therapy Cell Line, Tumor Cell Proliferation / drug effects Cytotoxicity, Immunologic / drug effects Disease Progression Female Gene Deletion Granzymes / metabolism Immunity / drug effects Immunotherapy Melanoma / pathology Membrane Proteins / metabolism Mice, Inbred C57BL Neoplasms / immunology prevention & control therapy Serpins / metabolism Small Molecule Libraries / pharmacology Stromal Cells / drug effects pathology Tumor Microenvironment / drug effects
来 源:
DOI:10.1016/j.cell.2020.10.045
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