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Abstract：
The most widely accepted theory for the development of preeclampsia is the \"two-stage theory\". An imbalance between antiangiogenic and proangiogenic factors is considered the link between the two stages. Nowadays, an increasing amount of data is available on the use of measurements of serum concentrations of these factors in the prediction, diagnosis and management of preeclampsia. The most useful, modern biochemical test that may help in making crucial clinical decisions in patients with preeclampsia is the sFlt-1/PlGF (soluble fms-like tyrosine kinase 1/placental growth factor) ratio. The aim of this review is to present the current use of different biochemical tests in the prediction, diagnosis and management of preeclampsia. Development of these diagnostic methods in recent years and a belief in their ground-breaking role in modern management of preeclampsia make this review especially important.
摘要：
关于先兆子痫发展的最广泛接受的理论是“两阶段理论”。抗血管生成因子和促血管生成因子之间的不平衡被认为是两个阶段之间的联系。如今,关于在预测中使用这些因素的血清浓度测量的数据越来越多，子痫前期的诊断和治疗。最有用的,可能有助于先兆子痫患者做出关键临床决定的现代生化检测是sFlt-1/PlGF(可溶性fms样酪氨酸激酶1/胎盘生长因子)比值.这篇综述的目的是介绍目前在预测中使用不同的生化测试，子痫前期的诊断和治疗。近年来这些诊断方法的发展以及对其在先兆子痫的现代管理中的突破性作用的信念使这篇综述尤其重要。
