关键词: Bence Jones protein amyloidosis multiple myeloma plasma cell dyscrasia serum free light chains urine immunofixation

来  源:   DOI:10.1515/dx-2020-0104   PDF(Sci-hub)

Abstract:
Testing urine for Bence Jones Protein (BJP) had been a time old procedure used for screening and monitoring of monoclonal disorders since its description. However, has poor sensitivity and despite advances in diagnostic methods of monoclonal disorders it is being continued to be requested in individuals for evaluation of myeloma or plasma cell disorders. Effective utilization and minimizing untimely or unnecessary investigations is important in the evaluation and management of any medical condition. Though, we are hard-wired during our education with some \"trigger\" or \"peculiar\" words that make us jump to actions too quickly, without comprehending the actual problem. Supporting evidence is presented to avoid reflexive use of multiple tests and utilize tests that improve utilization, reduce waste, and uphold the Choosing Wisely principles in providing optimal care to the patients.
摘要:
自描述以来,测试尿液中的BenceJones蛋白(BJP)一直是用于筛查和监测单克隆疾病的古老程序。然而,敏感性差,尽管单克隆疾病诊断方法取得了进展,但仍继续要求个体进行骨髓瘤或浆细胞疾病的评估。有效利用和尽量减少不及时或不必要的调查是重要的评估和管理的任何医疗条件。不过,在我们的教育过程中,我们有一些“触发”或“奇特”的单词,让我们太快地采取行动,不理解实际问题。提供支持证据,以避免反身使用多个测试,并利用提高利用率的测试,减少浪费,并坚持明智选择原则,为患者提供最佳护理。
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