关键词: Camelid SARS-CoV-2 diagnostic heavy-chain antibody therapeutic

Mesh : COVID-19 Humans SARS-CoV-2 Single-Domain Antibodies

来  源:   DOI:10.1080/07391102.2020.1845801   PDF(Sci-hub)   PDF(Pubmed)

Abstract:
Coronavirus disease 2019 (COVID-19) is a highly contagious disease caused by severe acute respiratory coronavirus 2 (SARS-CoV-2). This virus is capable of human-to-human transmission, and is spreading rapidly round the globe, with markedly high fatality rates. Unfortunately, there are neither vaccines nor specific therapies available to combat it, and the developments of such approaches depend on pursuing multiple avenues in biomedical science. Accordingly, in this paper we highlight one such avenue-nanobodies-for potential utility in therapeutic and diagnostic interventions to combat COVID-19.Communicated by Ramaswamy H. Sarma.
摘要:
2019年冠状病毒病(COVID-19)是一种由严重急性呼吸道冠状病毒2(SARS-CoV-2)引起的高度传染性疾病。这种病毒能够在人与人之间传播,并在全球迅速传播,死亡率明显很高。不幸的是,既没有疫苗也没有特定的疗法来对抗它,这种方法的发展取决于生物医学科学的多种途径。因此,在本文中,我们强调了一个这样的途径-纳米抗体-在对抗COVID-19的治疗和诊断干预中的潜在效用。由RamaswamyH.Sarma沟通。
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