PDF(Pubmed)
Abstract：
The aim of the present study is to investigate embryo quality (score) after controlled ovarian stimulation for IVF using rFSH or hMG with the GnRH antagonist protocol.
Open, randomized, single center study. The patients were randomized to receive rFSH or hMG according to randomized cards inside a black envelope with the name of the respective treatment following a computer generated list (85 patients were allocated to rFSH group and 83 patients to hMG group). Inclusion criteria were patients with IVF indication and normal ovarian reserve. Embryo evaluation was performed on day three, after fertilization based on the Graduated Embryo Score (GES).
There were no relevant differences in demographic characteristics. There was no difference in pregnancy rates with 27 (31%) and 25 (30.1%) pregnancies for rFSH and hMG, respectively (p=0.87). The total embryo score was the same for both groups, but the best embryo score was significant higher for the rFSH group (77.33±34.0 x 65.07±33.2 p=0.03). The total number of embryos was statistical different, also in favor of the rFSH group (4.17±3.1 x 3.26±2.4 p=0.04).
The total embryo score was the same for both groups, but the best embryo score was significantly higher for the rFSH group. Moreover, rFSH was associated with an increased number of embryos.
Open, randomized, single center study. The patients were randomized to receive rFSH or hMG according to randomized cards inside a black envelope with the name of the respective treatment following a computer generated list (85 patients were allocated to rFSH group and 83 patients to hMG group). Inclusion criteria were patients with IVF indication and normal ovarian reserve. Embryo evaluation was performed on day three, after fertilization based on the Graduated Embryo Score (GES).
There were no relevant differences in demographic characteristics. There was no difference in pregnancy rates with 27 (31%) and 25 (30.1%) pregnancies for rFSH and hMG, respectively (p=0.87). The total embryo score was the same for both groups, but the best embryo score was significant higher for the rFSH group (77.33±34.0 x 65.07±33.2 p=0.03). The total number of embryos was statistical different, also in favor of the rFSH group (4.17±3.1 x 3.26±2.4 p=0.04).
The total embryo score was the same for both groups, but the best embryo score was significantly higher for the rFSH group. Moreover, rFSH was associated with an increased number of embryos.
摘要：
本研究的目的是研究使用rFSH或hMG与GnRH拮抗剂方案进行IVF的受控卵巢刺激后的胚胎质量（评分）。
打开,随机化，单中心研究。根据计算机生成的列表（85名患者分配到rFSH组，83名患者分配到hMG组），根据黑色信封内的随机卡随机接受rFSH或hMG。纳入标准为IVF指征和卵巢储备正常的患者。在第三天进行胚胎评估，受精后基于分化胚胎评分（GES）。
人口统计学特征没有相关差异。rFSH和hMG妊娠率分别为27例(31%)和25例(30.1%),分别(p=0.87)。两组的胚胎总评分相同，但rFSH组的最佳胚胎评分明显较高（77.33±34.0x65.07±33.2p=0.03）。胚胎总数有统计学差异，也有利于rFSH组(4.17±3.1x3.26±2.4p=0.04)。
两组胚胎总评分相同，但rFSH组的最佳胚胎评分明显较高。此外，rFSH与胚胎数量的增加有关。
打开,随机化，单中心研究。根据计算机生成的列表（85名患者分配到rFSH组，83名患者分配到hMG组），根据黑色信封内的随机卡随机接受rFSH或hMG。纳入标准为IVF指征和卵巢储备正常的患者。在第三天进行胚胎评估，受精后基于分化胚胎评分（GES）。
人口统计学特征没有相关差异。rFSH和hMG妊娠率分别为27例(31%)和25例(30.1%),分别(p=0.87)。两组的胚胎总评分相同，但rFSH组的最佳胚胎评分明显较高（77.33±34.0x65.07±33.2p=0.03）。胚胎总数有统计学差异，也有利于rFSH组(4.17±3.1x3.26±2.4p=0.04)。
两组胚胎总评分相同，但rFSH组的最佳胚胎评分明显较高。此外，rFSH与胚胎数量的增加有关。
