关键词: Anti-proliferation activity HSP90-CDC37 Kinase maturation Protein-protein interaction inhibitors
Mesh : Animals Antineoplastic Agents / chemistry pharmacology Cell Cycle Proteins / metabolism Cell Proliferation / drug effects Chaperonins / metabolism Drug Design HCT116 Cells HSP90 Heat-Shock Proteins / metabolism Humans Hydrophobic and Hydrophilic Interactions / drug effects Mice Models, Molecular Neoplasms / drug therapy metabolism Protein Interaction Maps / drug effects
来 源:
DOI:10.1016/j.ejmech.2020.112959
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