诱饵纳米颗粒通过同时吸附病毒和炎性细胞因子来预防 COVID - 19 。
关键词: COVID-19 SARS-CoV-2 cell membrane vesicle cytokine storm nanodecoy
Mesh : Angiotensin-Converting Enzyme 2 Animals Betacoronavirus COVID-19 Cell Membrane / chemistry Coronavirus Infections / therapy Cytokines / antagonists & inhibitors Granulocyte-Macrophage Colony-Stimulating Factor / antagonists & inhibitors HEK293 Cells Humans Interleukin-6 / antagonists & inhibitors Mice Mice, Inbred ICR Monocytes Nanoparticles / chemistry therapeutic use Pandemics Peptidyl-Dipeptidase A / metabolism Pneumonia, Viral / therapy Receptors, Cytokine / metabolism SARS-CoV-2 THP-1 Cells Virus Internalization / drug effects
来 源:
DOI:10.1073/pnas.2014352117
PDF(Sci-hub)
PDF(Pubmed)