关键词: Extramedullary hematopoiesis Histiocytic Mastocytosis Myeloid Myeloproliferative neoplasm Spleen

Mesh : Dendritic Cells Humans Mast Cells Neoplasms Spleen Splenectomy Splenomegaly

来  源:   DOI:10.1053/j.semdp.2020.07.003

Abstract:
Splenic involvement and consequent splenomegaly are usually seen as part of systemic involvement by myeloid neoplasms as well as mast cell and histiocytic neoplasms. Primary splenic involvement by these neoplasms is rare. Splenectomy is usually not performed for establishing a diagnosis of these entities. However, in rare instances, the pathologist may need to evaluate the spleen secondary to splenic rupture or palliative splenectomy to alleviate symptoms related to splenomegaly. This review article describes the clinicopathologic features of a broad group of myeloid, mastocytic, and histiocytic proliferative and neoplastic disorders.
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