Abstract:
The purpose of this article is to overview the existing breast cancer screening guidelines for women at high risk from world-leading specialty societies. Accumulation of evidence and development of accessible genetic testing strategies have changed the idea of breast cancer screening for high-risk women. Personalized tailor-made screening adjusted for risk factors has been conducted in accordance with guidelines. The use of imaging modalities other than mammography including contrast-enhanced MRI and other various strategies for improving screening are discussed. The present review also mentions the existing challenges in high-risk screening and the latest information based on two large-scale studies.
摘要:
本文的目的是概述世界领先的专业协会针对高危女性的现有乳腺癌筛查指南。证据的积累和可访问的基因检测策略的发展改变了对高危女性进行乳腺癌筛查的想法。已根据指南进行了针对风险因素进行调整的个性化定制筛查。讨论了乳房X线照相术以外的成像方式的使用,包括对比增强MRI和其他各种改善筛查的策略。本综述还提到了高风险筛查中存在的挑战以及基于两项大规模研究的最新信息。