关键词: Asenapine Cytochrome P450 expression inhibition Drug-drug interactions Human hepatocytes Iloperidone Lurasidone
Mesh : Antipsychotic Agents / pharmacology Cell Survival / drug effects Cells, Cultured Cytochrome P-450 Enzyme Inhibitors / pharmacology Cytochrome P-450 Enzyme System / genetics metabolism Dibenzocycloheptenes Drug Interactions Hepatocytes / drug effects metabolism Heterocyclic Compounds, 4 or More Rings / pharmacology Humans Isoxazoles / pharmacology L-Lactate Dehydrogenase / metabolism Lurasidone Hydrochloride / pharmacology Piperidines / pharmacology RNA, Messenger / metabolism
来 源:
DOI:10.1016/j.taap.2020.115239
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