关键词: Cutaneous toxicity ethambutol extrapulmonary tuberculosis testicular tuberculosis

Mesh : Antitubercular Agents / therapeutic use toxicity Ethambutol / toxicity Humans Male Middle Aged Skin / drug effects pathology Testicular Diseases / drug therapy microbiology Testis / diagnostic imaging pathology Tuberculosis / complications diagnosis drug therapy Ultrasonography

来  源:   DOI:10.4103/ijmy.ijmy_114_20

Abstract:
Tuberculosis (TB) is an infection that can affect any organ, affecting mainly the lungs. Isolated testicular TB is very rare. Six months of a multiple drug scheme is the mainstay of TB treatment. Adverse reaction to anti-TB chemotherapy is frequent and affects the course of the therapy, leading sometimes to discontinuation of drugs. Ethambutol optic nerve toxicity is frequent. However, severe cutaneous and anaphylactic reactions associated to ethambutol are very rare. We present the case of an immunocompetent patient presenting with isolated testicular TB that exhibited a severe cutaneous and anaphylactic reaction to ethambutol during the consolidation treatment phase. This led to exhaustive etiologic study and treatment modification.
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