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Abstract：
Syphilis, a sexually transmitted disease, can be categorized as acquired syphilis and congenital syphilis, manifesting diverse lesions involving multiple sites. Oral manifestations at the primary stage of acquired syphilis are usually characterized by its short period and non-specific varied presentations. And oral ulcers as initial and the only presentation of syphilis oral lesions are infrequent and occur in less than 2% of patients. Because of its transient nature and variable manifestations which could mimic other oral ulcerative lesions, oral syphilis presenting as sole ulceration at early stage can be easily neglected and rather difficult to diagnose. Herein, we report a 35-year-old female patient manifested a sole atypical ulceration on her upper lip for approximately 1 month. We highlighted the importance of early and accurate diagnosis, focused on the characteristics of oral chancre, and gave an insight to the differential diagnoses, which would be enlightening and useful in clinical practice.
摘要：
梅毒,一种性传播疾病,可以分为获得性梅毒和先天性梅毒，表现出涉及多个部位的多种病变。获得性梅毒初期的口腔表现通常以短暂且非特异性的变化表现为特征。并且口腔溃疡作为梅毒口腔病变的初始和唯一表现很少见，并且发生在不到2％的患者中。由于其短暂的性质和可变的表现，可以模仿其他口腔溃疡病变，在早期表现为唯一溃疡的口腔梅毒很容易被忽略，并且很难诊断。在这里，我们报告一名35岁的女性患者，在她的上唇上表现为唯一的不典型溃疡约1个月。我们强调了早期准确诊断的重要性，专注于口腔下颌的特点，并深入了解了鉴别诊断，这将是启发和有用的临床实践。
