Abstract：
Pediatric aggressive mature B-cell lymphomas are the most common types of non-Hodgkin lymphoma in children, and they include Burkitt lymphoma (BL) and diffuse large B-cell lymphoma (DLBCL). These diseases are highly aggressive but curable, the treatment is complex, and patients may have many complicated supportive care issues. The NCCN Guidelines for Pediatric Aggressive Mature B-Cell Lymphomas provide guidance regarding pathology and diagnosis, staging, initial treatment, disease reassessment, surveillance, therapy for relapsed/refractory disease, and supportive care for clinicians who treat sporadic pediatric BL and DLBCL.
摘要：
儿童侵袭性成熟B细胞淋巴瘤是儿童非霍奇金淋巴瘤最常见的类型，包括伯基特淋巴瘤（BL）和弥漫性大B细胞淋巴瘤（DLBCL）。这些疾病具有很强的攻击性，但可以治愈，治疗很复杂,患者可能有许多复杂的支持性护理问题。儿童侵袭性成熟B细胞淋巴瘤的NCCN指南为病理学和诊断提供了指导。分期,初始治疗,疾病重新评估，监视,治疗复发/难治性疾病，以及对治疗散发性小儿BL和DLBCL的临床医生的支持治疗。
