Acute Necrotizing Encephalopathy of Childhood with H1N1 Infection.

• 发表时间: Sep 2020
• 来源期刊: J Pediatr Intensive Care
• DOI: 10.1055/s-0040-1705182
• PMID: 32685254
• 文章类型: Case Reports
• 作者列表: Takia L,Patra N,Nallasamy K,Saini L,Suthar R,Angurana SK,Jayashree M

关键词: H1N1 influenza; encephalopathy; raised ICP

Abstract

Acute necrotizing encephalopathy of childhood (ANEC) is an uncommon and fulminant complication of seasonal influenza infection associated with high mortality and poor neurological outcome. We report a 4.5-year-old female who had pneumonia, ANEC, and raised intracranial pressure (ICP) with polymerase chain reaction proven H1N1 infection. Management included mechanical ventilation, invasive monitoring and control of ICP, oseltamivir, methylprednisolone, and supportive care in pediatric intensive care unit. She survived with poor neurological status at discharge.