关键词: Crohn’s disease Gastric signet ring cells carcinoma Lymphoma Rituximab

Mesh : Anti-Inflammatory Agents / therapeutic use Antineoplastic Agents, Immunological / adverse effects Budesonide / therapeutic use Carcinoma, Signet Ring Cell / diagnosis drug therapy immunology Crohn Disease / chemically induced diagnosis drug therapy immunology Drug Therapy, Combination / methods Humans Induction Chemotherapy / adverse effects methods Lymphoma, Follicular / diagnosis drug therapy immunology Maintenance Chemotherapy / adverse effects methods Male Mesalamine / therapeutic use Middle Aged Neoplasms, Multiple Primary / diagnosis drug therapy immunology Rituximab / adverse effects Stomach Neoplasms / drug therapy immunology Treatment Outcome

来  源:   DOI:10.4143/crt.2020.406   PDF(Pubmed)

Abstract:
Recently, there have been a few reports of rituximab (RTX)-induced Crohn\'s disease, but there is no literature available on successful long-term treatment and the clinical outcome of this condition. We retrospectively analyzed the clinical data of a rare case of Crohn\'s disease induced by RTX administered as induction and prolonged maintenance therapy of a follicular lymphoma, diagnosed synchronously with a gastric signet ring cells carcinoma, treated at our hospital.
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