PDF(Sci-hub)
Abstract：
Waldeyer\'s ring (WR) involvement in pediatric Hodgkin lymphoma (HL) is extremely rare and criteria for determining involvement and response to treatment are unclear. The international Staging, Evaluation, and Response Criteria Harmonization for Childhood, Adolescent and Young Adult Hodgkin Lymphoma (SEARCH for CAYAHL) Group performed a systematic review of the literature in search of involvement or response criteria, or evidence to support specific criteria. Only 166 cases of HL with WR involvement were reported in the literature, 7 of which were pediatric. To date no standardized diagnostic or response assessment criteria are available. Given the paucity of evidence, using a modified Delphi survey technique, expert consensus statements were developed by the SEARCH group to allow for a more consistent definition of disease and response evaluation related to this rare site of involvement among pediatric oncologists. The available evidence and expert consensus statements are summarized.
摘要：
儿童霍奇金淋巴瘤（HL）的Waldeyer环（WR）受累极为罕见，确定受累和治疗反应的标准尚不清楚。国际舞台，评价,和儿童应对标准协调，青少年和年轻成人霍奇金淋巴瘤（SEARCHforCAYAHL）小组对文献进行了系统回顾，以寻找受累或反应标准，或支持特定标准的证据。文献中仅报道了166例累及WR的HL，其中7人是儿科。迄今为止，尚无标准化的诊断或反应评估标准。鉴于证据不足,使用改进的德尔菲调查技术，专家共识声明由SEARCH小组制定,以便在儿科肿瘤学家中对与这一罕见受累部位相关的疾病和应答评估进行更一致的定义.总结了现有证据和专家共识声明。
