Abstract:
The attentional blink (AB) has been central in characterizing the limit of temporal attention and consciousness. The neural mechanism of the AB is still in hot debate. With a large sample size, we combined multiple behavioral tests, multimodal MRI measures, and transcranial magnetic stimulation to investigate the neural basis underlying the individual differences in the AB. We found that AB magnitude correlated with the executive control functioning of working memory (WM) in behavior, which was fully mediated by T1 performance. Structural variations in the right temporoparietal junction (rTPJ) and its intrinsic functional connectivity with the left inferior frontal junction (lIFJ) accounted for the individual differences in the AB, which was moderated by the executive control of working memory. Disrupting the function of the lIFJ attenuated the AB deficit. Our findings clarified the neural correlates of the individual differences in the AB and elucidated its relationship with the consolidation-driven inhibitory control process.
摘要:
注意眨眼(AB)一直是表征时间注意力和意识极限的核心。AB的神经机制至今仍是争论的热点。样本量大,我们结合了多个行为测试,多模态MRI测量,和经颅磁刺激来研究AB个体差异的神经基础。我们发现AB幅度与行为中工作记忆(WM)的执行控制功能相关,这完全由T1表现介导。右颞顶交界处(rTPJ)的结构变化及其与左下额叶交界处(lIFJ)的内在功能连通性占AB的个体差异,这是通过工作记忆的执行控制来调节的。破坏lIFJ的功能减轻了AB缺陷。我们的发现阐明了AB中个体差异的神经相关性,并阐明了其与巩固驱动的抑制控制过程的关系。