Mesh : Blastomyces / isolation & purification Blastomycosis / diagnosis therapy Bone Diseases / diagnosis microbiology therapy Female Humans Middle Aged

来  源:   DOI:10.2106/JBJS.CC.19.00553   PDF(Sci-hub)

Abstract:
We describe a case of biopsy-proven blastomycosis in a patient residing in Upstate New York with osseous and skin lesions and no pulmonary or constitutional symptoms. The patient had a rapid resolution of symptoms after the initiation of antifungal treatment, followed by curettage and cementation of her distal femoral lesion.
Orthopaedic surgeons should be aware of the presence of blastomycosis in nonendemic areas, especially since bone involvement may be the predominant manifestation. Tissue should be submitted for both histologic and microbiologic analysis. Antifungal therapy and surgical management if needed can result in a good outcome.
摘要:
我们描述了居住在纽约州北部的一名患者的活检证实的芽生菌病,该患者有骨和皮肤病变,没有肺部或全身症状。开始抗真菌治疗后,患者症状迅速缓解,然后对她的股骨远端病变进行刮除和骨水泥处理。
骨科医生应该意识到非流行地区有芽生菌病的存在,尤其是骨受累可能是主要表现。组织应进行组织学和微生物分析。抗真菌治疗和手术管理,如果需要可以产生良好的结果。
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