关键词: Hypomyopathic dermatomyositis Low-dose IL-2 Refractory dermatitis

来  源:   DOI:10.1007/s13555-020-00421-8   PDF(Pubmed)

Abstract:
Hypomyopathic dermatomyositis (DM) presents with cutaneous lesions consistent with dermatomyositis but in the absence of clinically appreciable muscle weakness. The cutaneous manifestations are often refractory and more resistant to conventional therapy than concomitant muscle involvement. We present a 61-year-old hypomyopathic patient with DM who failed to respond to standard therapy but was successfully treated by low-dose interleukin-2 (IL-2) with no significant side effects. We conclude that low-dose IL-2 is a safe and effective treatment for hypomyopathic DM.
摘要:
低肌病性皮肌炎(DM)表现为与皮肌炎一致的皮肤病变,但没有临床上明显的肌肉无力。与伴随的肌肉受累相比,皮肤表现通常是难治性的,并且对常规治疗更具抵抗力。我们介绍了一名61岁的DM低肌病性患者,该患者对标准疗法无反应,但成功接受了低剂量白介素2(IL-2)的治疗,没有明显的副作用。我们得出的结论是,低剂量IL-2是低肌病性DM的安全有效治疗方法。
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