关键词: Impetigo herpetiformis erythema induced labor pregnancy pustule skin disease

Mesh : Abortion, Induced / methods Adrenal Cortex Hormones Adult China Ethacridine / pharmacology Female Humans Immunosuppressive Agents Impetigo / complications mortality therapy Pregnancy Psoriasis / complications

来  源:   DOI:10.1177/0300060520933811   PDF(Sci-hub)   PDF(Pubmed)

Abstract:
Impetigo herpetiformis is a rare variant of generalized pustular psoriasis that occurs during pregnancy or is triggered by pregnancy, often in association with hypocalcemia. This condition is associated with increased maternal and fetal morbidity and mortality. We report a 29-year-old pregnant woman who presented to hospital at the gestational age of 20 weeks with widespread erythema covered with pustules that coalesced to form lakes of pus. She did not respond to corticosteroids, immunosuppressants, or phototherapy. Finally, intra-amniotic injection of ethacridine lactate was administered to terminate the pregnancy, and the patient showed complete recovery in 3 months. Insight from this case report may facilitate optimal management of this relatively rare entity.
摘要:
疱疹样脓疱疮是在怀孕期间发生或由怀孕引发的全身性脓疱性牛皮癣的罕见变体,常伴有低钙血症。这种情况与母亲和胎儿发病率和死亡率增加有关。我们报告了一名29岁的孕妇,她在20周胎龄时住院,广泛的红斑覆盖着脓疱,合并形成脓湖。她对皮质类固醇没有反应,免疫抑制剂,或者光疗。最后,羊膜腔内注射乳酸依沙吖啶以终止妊娠,患者在3个月内完全康复。从这个案例报告的洞察力可以促进这个相对罕见的实体的最佳管理。
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