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Abstract：
Post-inflammatory hyperpigmentation (PIH) is a common adverse effect of laser hair removal procedures. This case series emphasizes the under-reported crescent-shaped form of PIH that may occur following laser therapy. This case series sought to assess the potential causes of the distinct, crescent-shaped form of PIH that may arise following laser hair removal procedures, and to examine the concept of thermal versus cryogenic damage, which was discovered accidentally due misalignments between laser-cryogen spurts.
A retrospective, multicentre case recruitment was undertaken, involving three laser centers and presented in the form of a case series. The included patients were individuals with crescent-shaped PIH following laser hair removal.
Fifteen patients were recruited over 12 months. All patients were treated with the GentleLase system (Candella) with built-in cryogen spurt. Prior to the study, only one patient had suffered from PIH following laser hair removal. Most patients improved partially or completely both with and without the use of bleaching compounds. After testing one machine, it was found that the cryogen spurt was misaligned. It was not located in the circle of the laser beam, thereby leaving a crescent shape of uncooled but laser-treated skin. A trial on one patient with cryogen alone did not cause PIH, whereas a trial with the laser alone caused PIH.
The appearance of crescent-shaped marks following PIH is a distinct and uncommon adverse effect associated with laser hair removal procedures. This case series suggests that it arises due to the malfunctioning of the built-in cryogen spurt device, leading to a deficit in cooling a portion of the treated skin, urging checking the built-in cryogen spurt device. Lasers Surg. Med. © 2020 Wiley Periodicals, LLC.
A retrospective, multicentre case recruitment was undertaken, involving three laser centers and presented in the form of a case series. The included patients were individuals with crescent-shaped PIH following laser hair removal.
Fifteen patients were recruited over 12 months. All patients were treated with the GentleLase system (Candella) with built-in cryogen spurt. Prior to the study, only one patient had suffered from PIH following laser hair removal. Most patients improved partially or completely both with and without the use of bleaching compounds. After testing one machine, it was found that the cryogen spurt was misaligned. It was not located in the circle of the laser beam, thereby leaving a crescent shape of uncooled but laser-treated skin. A trial on one patient with cryogen alone did not cause PIH, whereas a trial with the laser alone caused PIH.
The appearance of crescent-shaped marks following PIH is a distinct and uncommon adverse effect associated with laser hair removal procedures. This case series suggests that it arises due to the malfunctioning of the built-in cryogen spurt device, leading to a deficit in cooling a portion of the treated skin, urging checking the built-in cryogen spurt device. Lasers Surg. Med. © 2020 Wiley Periodicals, LLC.
摘要：
炎症后色素沉着过度(PIH)是激光脱毛手术的常见不良反应。本病例系列强调了激光治疗后可能发生的PIH的新月形形式报道不足。这个案例系列试图评估不同的潜在原因，激光脱毛手术后可能出现的新月形PIH，并研究热损伤与低温损伤的概念，这是由于激光冷冻剂喷射之间的不对准而意外发现的。
回顾,进行了多中心病例招募，涉及三个激光中心，并以案例系列的形式呈现。所包括的患者是激光脱毛后患有新月形PIH的个体。
在12个月内招募了15名患者。所有患者均采用内置冷冻剂喷射的GentleLase系统（Candella）进行治疗。在研究之前,只有1例患者在激光脱毛后出现PIH.大多数患者在使用和不使用漂白化合物的情况下部分或完全改善。测试一台机器后，结果发现冷冻剂喷出错位。它不在激光束的圆圈中，从而留下未冷却但经过激光治疗的皮肤的新月形。对一名单独使用冷冻剂的患者进行的试验并未导致PIH，而仅使用激光进行的试验导致了PIH。
在PIH之后出现新月形标记是与激光脱毛程序相关的明显且不常见的不利影响。本系列病例表明，它是由于内置低温喷射装置的故障引起的，导致一部分治疗皮肤的冷却不足，敦促检查内置的冷冻剂喷射装置。激光器Surg.Med.©2020威利期刊，LLC.
回顾,进行了多中心病例招募，涉及三个激光中心，并以案例系列的形式呈现。所包括的患者是激光脱毛后患有新月形PIH的个体。
在12个月内招募了15名患者。所有患者均采用内置冷冻剂喷射的GentleLase系统（Candella）进行治疗。在研究之前,只有1例患者在激光脱毛后出现PIH.大多数患者在使用和不使用漂白化合物的情况下部分或完全改善。测试一台机器后，结果发现冷冻剂喷出错位。它不在激光束的圆圈中，从而留下未冷却但经过激光治疗的皮肤的新月形。对一名单独使用冷冻剂的患者进行的试验并未导致PIH，而仅使用激光进行的试验导致了PIH。
在PIH之后出现新月形标记是与激光脱毛程序相关的明显且不常见的不利影响。本系列病例表明，它是由于内置低温喷射装置的故障引起的，导致一部分治疗皮肤的冷却不足，敦促检查内置的冷冻剂喷射装置。激光器Surg.Med.©2020威利期刊，LLC.
