PDF(Pubmed)
Abstract：
Since its origin in China, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has become a pandemic and spread to 209 countries. As coronavirus disease 2019 (COVID-19) is a very rapidly emerging disease, organ-specific studies related to it have been reported. Apart from respiratory findings, some studies have highlighted inflammatory consequences in the heart, kidney, and/or liver as well. Cardiac involvement in COVID-19 seems to be a result of an inflammatory storm in response to the infection. Moreover, direct viral invasion of cardiomyocytes, as well as a myocardial injury due to oxidative stress, may account for acute cardiac injury in COVID-19. Nevertheless, the mechanism of heart injury in COVID-19 is not clear yet. However, multiple studies that highlight the clinical features, laboratory findings, and prognosis of acute myocardial injury (AMI) in COVID-19-affected individuals have been published. In this review, we have summarized the findings of all those studies as well as the clinical features and management of cardiac injury discussed by some case reports.
摘要：
自从它起源于中国，严重急性呼吸道综合症冠状病毒2（SARS-CoV-2）感染已成为一种流行病，并传播到209个国家。由于2019年冠状病毒病(COVID-19)是一种非常迅速出现的疾病，已经报道了与之相关的器官特异性研究。除了呼吸道检查结果,一些研究强调了心脏的炎症后果，肾,和/或肝脏。COVID-19的心脏受累似乎是对感染的炎症风暴的结果。此外，直接病毒侵入心肌细胞，以及由于氧化应激引起的心肌损伤，可能是COVID-19急性心脏损伤的原因。然而，COVID-19的心脏损伤机制尚不清楚。然而,多项研究突出了临床特征，实验室发现,和COVID-19感染个体的急性心肌损伤（AMI）的预后已发表。在这次审查中,我们总结了所有这些研究的结果，以及一些病例报告中讨论的心脏损伤的临床特征和处理。
