Abstract:
As an alternative to autologous nerve donors, acellular nerve allografts (ANAs) have been studied in many experiments. There have been numerous studies on processing ANAs and various studies on the clinical applications of ANA, but there have not been many studies on sources of ANAs. The purposes of the present study were to evaluate the course of the saphenous and sural nerves in human cadavers and help harvest auto- or allografts for clinical implications. Eighteen lower extremities of 16 fresh cadavers were dissected. For the saphenous nerve and sural nerve, the distances between each branch and the diameters at the midpoint between each branch were measured. In the saphenous nerve, the mean length between each branch ranged from 7.2 to 28.6 cm, and the midpoint diameter ranged from 1.4 to 3.2 mm. In the sural nerve, the mean length between each branch ranged from 17.4 to 21 cm, and the midpoint diameter ranged from 2.3 to 2.8 mm. The present study demonstrates the length of the saphenous and sural nerve without branches with diameters larger than 1 mm. With regard for the clinical implications of allografts, the harvest of a selective nerve length with a large enough diameter could be possible based on the data presented in the present study.
摘要:
作为自体神经供体的替代方案,脱细胞神经同种异体移植物(ANA)已在许多实验中进行了研究。关于ANA的加工和临床应用的各种研究已经有了大量的研究,但是关于ANAs来源的研究并不多。本研究的目的是评估人类尸体中隐神经和腓肠神经的过程,并帮助收获自体或同种异体移植物以达到临床意义。解剖了16具新鲜尸体的18个下肢。对于隐神经和腓肠神经,测量每个分支之间的距离和每个分支之间中点的直径。在隐神经中,每个分支之间的平均长度范围为7.2至28.6厘米,中点直径为1.4~3.2mm。在腓肠神经中,每个分支之间的平均长度范围为17.4至21厘米,中点直径范围为2.3至2.8毫米。本研究证明了隐神经和腓肠神经的长度,没有直径大于1毫米的分支。关于同种异体移植物的临床意义,根据本研究提供的数据,可以获得具有足够大直径的选择性神经长度。