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Abstract：
BACKGROUND: The aim of this study is to explore the effect of grelin on TRX expression (TRXE) in chronic heart failure tissue (CHFT).
METHODS: We will search electronic databases from inception to the March 1, 2020 in MEDLINE, EMBASE, Cochrane Library, CINAHL, PEDro, the Allied and Complementary Medicine Database, Chinese Biomedical Literature Database, and China National Knowledge Infrastructure. We will not apply any limitations to the language and publication status. Any randomized controlled trials (RCTs) that studied the effect of grelin on TRXE in CHFT will be included. Study quality will be checked by Cochrane risk of bias and evidence quality will be appraised by Grading of Recommendations Assessment Development and Evaluation. All extracted data will be analyzed by RevMan 5.3 Software.
RESULTS: This study will summarize the present RCTs to assess the effect of grelin on TRXE in CHFT.
CONCLUSIONS: The results of this study will provide conclusive evidence of the effect of grelin on TRXE in CHFT.
BACKGROUND: INPLASY202040078.
METHODS: We will search electronic databases from inception to the March 1, 2020 in MEDLINE, EMBASE, Cochrane Library, CINAHL, PEDro, the Allied and Complementary Medicine Database, Chinese Biomedical Literature Database, and China National Knowledge Infrastructure. We will not apply any limitations to the language and publication status. Any randomized controlled trials (RCTs) that studied the effect of grelin on TRXE in CHFT will be included. Study quality will be checked by Cochrane risk of bias and evidence quality will be appraised by Grading of Recommendations Assessment Development and Evaluation. All extracted data will be analyzed by RevMan 5.3 Software.
RESULTS: This study will summarize the present RCTs to assess the effect of grelin on TRXE in CHFT.
CONCLUSIONS: The results of this study will provide conclusive evidence of the effect of grelin on TRXE in CHFT.
BACKGROUND: INPLASY202040078.
摘要：
背景：本研究的目的是探讨grelin对慢性心力衰竭组织（CHFT）中TRX表达（TRXE）的影响。
方法：我们将在MEDLINE中搜索从成立到2020年3月1日的电子数据库，EMBASE,科克伦图书馆,CINAHL,PEDro,联合和补充医学数据库，中国生物医学文献数据库,和中国国家知识基础设施。我们不会对语言和出版状态施加任何限制。将包括研究Grelin对CHFT中TRXE的影响的任何随机对照试验（RCT）。研究质量将通过Cochrane偏差风险进行检查，证据质量将通过建议评估开发和评估的分级进行评估。所有提取的数据将通过RevMan5.3软件进行分析。
结果：本研究将总结目前的RCT，以评估格瑞林对CHFT中TRXE的影响。
结论：这项研究的结果将为格瑞林在CHFT中对TRXE的影响提供确凿证据。
背景：INPLASY202040078.
方法：我们将在MEDLINE中搜索从成立到2020年3月1日的电子数据库，EMBASE,科克伦图书馆,CINAHL,PEDro,联合和补充医学数据库，中国生物医学文献数据库,和中国国家知识基础设施。我们不会对语言和出版状态施加任何限制。将包括研究Grelin对CHFT中TRXE的影响的任何随机对照试验（RCT）。研究质量将通过Cochrane偏差风险进行检查，证据质量将通过建议评估开发和评估的分级进行评估。所有提取的数据将通过RevMan5.3软件进行分析。
结果：本研究将总结目前的RCT，以评估格瑞林对CHFT中TRXE的影响。
结论：这项研究的结果将为格瑞林在CHFT中对TRXE的影响提供确凿证据。
背景：INPLASY202040078.
