关键词: Lethal EMT NM23H1 Par-4 TGF-β/Smad4
Mesh : Carcinoma, Pancreatic Ductal / metabolism pathology Cell Line, Tumor Epithelial-Mesenchymal Transition G1 Phase Cell Cycle Checkpoints Humans NM23 Nucleoside Diphosphate Kinases / genetics metabolism Pancreatic Neoplasms / metabolism pathology Plasmids / genetics Proto-Oncogene Proteins c-akt / antagonists & inhibitors metabolism RNA, Small Interfering / administration & dosage genetics RNA-Binding Proteins / metabolism Receptors, Thrombin / genetics metabolism Signal Transduction Smad4 Protein / biosynthesis genetics metabolism Transforming Growth Factor beta / metabolism Up-Regulation
来 源:
DOI:10.1016/j.ejcb.2020.151076
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