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Abstract：
To date, studies of patients with islet transplantation addressing intermittently scanned continuous glucose monitoring profile and the flexibility of the graft islet function under different doses of insulin administration, both of which reflect the real daily life of patients, are quite limited. Here, we report a case of a 46-year-old woman who received islet transplantation after kidney transplantation. The patient was followed up over a period of 2 years after initial islet transplantation. Our results show that intermittently scanned continuous glucose monitoring can be useful for monitoring the reduction of glycemic variability, and suggest the appropriate regulation of insulin secretion from graft islets during mixed-meal test by using different doses of exogenous insulin administration. Additionally, during the 2-year observational period, glucagon elevation was detected only at hypoglycemia, whereas the level was within the normal range at normoglycemia or hyperglycemia.
摘要：
迄今为止,研究胰岛移植患者在不同剂量胰岛素给药的情况下解决间歇性扫描连续血糖监测曲线和移植胰岛功能的灵活性，两者都反映了患者的真实日常生活，是相当有限的。这里,我们报道一例46岁女性,她在肾移植后接受胰岛移植.初次胰岛移植后，对患者进行了2年的随访。我们的结果表明，间歇性扫描连续血糖监测可用于监测血糖变异性的降低，并建议通过使用不同剂量的外源性胰岛素给药，在混合餐试验中适当调节移植胰岛的胰岛素分泌。此外,在为期两年的观测期间，仅在低血糖时检测到胰高血糖素升高，而血糖正常或高血糖时该水平在正常范围内。
