Pheochromocytoma and paraganglioma are uncommon and are frequently overlooked in registry data sets. Malignant criteria have previously been defined only when there was metastatic disease.
With recent recognition of a significant inheritance association and the development of risk stratification tools, this data set was created in order to obtain more meaningful outcomes and management data, using similar criteria across the global pathology community. Issues related to key core and non-core elements, especially clinical hormonal status, familial history, tumor focality, proliferative fraction, adverse or risk stratification features, and ancillary techniques, are discussed in the context of daily application to these types of specimens.
The ICCR data set, developed by an international panel of endocrine organ specialists, establishes a pathology-standardized reporting guide for pheochromocytoma and paraganglioma.
嗜铬细胞瘤和副神经节瘤并不常见,在注册数据集中经常被忽视。以前只有在有转移性疾病时才定义恶性标准。
随着最近对重要遗传关联的认识和风险分层工具的发展,这个数据集的创建是为了获得更有意义的结果和管理数据,在全球病理学界使用类似的标准。与关键核心和非核心要素有关的问题,尤其是临床荷尔蒙状态,家族史,肿瘤病灶,增殖分数,不利或风险分层特征,和辅助技术,在这些类型的标本的日常应用的背景下进行讨论。
ICCR数据集,由国际内分泌器官专家小组开发,建立嗜铬细胞瘤和副神经节瘤的病理学标准化报告指南.