Abstract：
Platelet mass index (PMI) is calculated by multiplying platelet count and mean platelet volume (MPV). It demonstrates platelet activation and is thought to be associated with inflammation. Its importance for cardiac surgery has not yet fully been clarified. This study investigates whether there is a difference between PMI levels after on-pump and off-pump coronary artery bypass surgery and the relationship between early postoperative complications and PMI.
In our hospital, 138 patients were included in the study retrospectively. The patients were divided into 2 groups: Group 1 (on-pump) with 80 patients (22 females, 58 males, mean age 61.54 ± 8.68) and Group 2 (off-pump) with 58 patients (15 females, 43 males, mean age 61.34 ± 10.04). In biochemical analysis, hemoglobin, platelet, white blood cell, and MPV values of the patients were evaluated in the biochemistry laboratory of our hospital with the blood taken preoperatively from the forearm veins and postoperatively on the first, third, and seventh days and, on average, after the first month.
There was a statistically significant difference between postoperative first day thrombocyte (K/µL) (P = .005), postoperative first day PMI (P = .014), postoperative first day leukocyte (K/µL) (P = .001), postoperative first day Hb (g/dL) (P = .001), postoperative third day thrombocyte (K/µL) (P = .003), postoperative third day PMI (P = .031), postoperative third day leukocyte (K/µL) (P = .004), and postoperative seventh day leukocyte (K/µL) (P = .002). There was no meaningful relationship between PMI and early postoperative complications.
We think PMI is a more valuable indicator than MPV as an inflammation marker in cardiac surgery. In our opinion, PMI is a cheap and valuable inflammation marker that can be used in coronary surgery that can be obtained from routine hemogram test and can easily be evaluated.
In our hospital, 138 patients were included in the study retrospectively. The patients were divided into 2 groups: Group 1 (on-pump) with 80 patients (22 females, 58 males, mean age 61.54 ± 8.68) and Group 2 (off-pump) with 58 patients (15 females, 43 males, mean age 61.34 ± 10.04). In biochemical analysis, hemoglobin, platelet, white blood cell, and MPV values of the patients were evaluated in the biochemistry laboratory of our hospital with the blood taken preoperatively from the forearm veins and postoperatively on the first, third, and seventh days and, on average, after the first month.
There was a statistically significant difference between postoperative first day thrombocyte (K/µL) (P = .005), postoperative first day PMI (P = .014), postoperative first day leukocyte (K/µL) (P = .001), postoperative first day Hb (g/dL) (P = .001), postoperative third day thrombocyte (K/µL) (P = .003), postoperative third day PMI (P = .031), postoperative third day leukocyte (K/µL) (P = .004), and postoperative seventh day leukocyte (K/µL) (P = .002). There was no meaningful relationship between PMI and early postoperative complications.
We think PMI is a more valuable indicator than MPV as an inflammation marker in cardiac surgery. In our opinion, PMI is a cheap and valuable inflammation marker that can be used in coronary surgery that can be obtained from routine hemogram test and can easily be evaluated.
摘要：
通过将血小板计数和平均血小板体积(MPV)相乘来计算血小板质量指数(PMI)。它显示血小板活化并被认为与炎症有关。它对心脏手术的重要性尚未完全阐明。本研究调查了体外循环和非体外循环冠状动脉搭桥手术后PMI水平是否存在差异以及术后早期并发症与PMI的关系。
在我们医院,138例患者被纳入回顾性研究。将患者分为2组：第1组（在泵上）80例患者（22例女性，58名男性,平均年龄61.54±8.68）和第2组（非体外循环）58例患者（15例女性，43名男性，平均年龄61.34±10.04)。在生化分析中，血红蛋白,血小板,白细胞,患者的MPV值在我院生化实验室进行评估，术前从前臂静脉取血，第三,第七天，平均而言,第一个月之后。
术后第一天血小板（K/µL）之间存在统计学上的显着差异（P=0.005），术后第一天PMI（P=0.014），术后第一天白细胞（K/µL）（P=.001），术后第一天Hb（g/dL）（P=.001），术后第三天血小板（K/μL）（P=0.003），术后第3天PMI（P=0.031），术后第3天白细胞（K/μL）（P=.004），和术后第七天白细胞（K/µL）（P=0.002）。PMI与术后早期并发症无明显关系。
我们认为PMI作为心脏手术中的炎症标志物比MPV更有价值。在我们看来,PMI是一种廉价且有价值的炎症标志物，可用于冠状动脉手术，可从常规血象检查中获得，并易于评估。
在我们医院,138例患者被纳入回顾性研究。将患者分为2组：第1组（在泵上）80例患者（22例女性，58名男性,平均年龄61.54±8.68）和第2组（非体外循环）58例患者（15例女性，43名男性，平均年龄61.34±10.04)。在生化分析中，血红蛋白,血小板,白细胞,患者的MPV值在我院生化实验室进行评估，术前从前臂静脉取血，第三,第七天，平均而言,第一个月之后。
术后第一天血小板（K/µL）之间存在统计学上的显着差异（P=0.005），术后第一天PMI（P=0.014），术后第一天白细胞（K/µL）（P=.001），术后第一天Hb（g/dL）（P=.001），术后第三天血小板（K/μL）（P=0.003），术后第3天PMI（P=0.031），术后第3天白细胞（K/μL）（P=.004），和术后第七天白细胞（K/µL）（P=0.002）。PMI与术后早期并发症无明显关系。
我们认为PMI作为心脏手术中的炎症标志物比MPV更有价值。在我们看来,PMI是一种廉价且有价值的炎症标志物，可用于冠状动脉手术，可从常规血象检查中获得，并易于评估。
