Abstract：
Nevus sebaceus is a benign skin hamartoma of congenital onset that grows during puberty, and in adulthood can develop secondary benign and malignant neoplasms. The most common benign neoplasms occurring in nevus sebaceus are believed to be syringocystadenoma papilliferum, trichilemmoma, and trichoblastoma. A patient with nevus sebaceus developed not only syringocystadenoma papilliferum but also prurigo nodularis within her hamartomatous lesion; multiple biopsies were necessary to establish the diagnoses. Excision of the residual nevus sebaceus also revealed an apocrine cystadenoma, basaloid follicular proliferation, and sebaceoma. Also, it is important to select the appropriate biopsy site and size when evaluating a patient for secondary neoplasms within their nevus sebaceous. Indeed, more than one biopsy may be required if additional diagnoses are suspected.
摘要：
痣是一种先天性良性皮肤错构瘤，在青春期生长，在成年期可以发展继发性良性和恶性肿瘤。在痣中最常见的良性肿瘤被认为是乳头瘤的空洞囊腺瘤。三叶草,和成毛细胞瘤.患有痣的患者不仅发展为乳头状的紫癜囊腺瘤，而且在错构瘤病变内还发展为结节性pur。需要进行多次活检才能确定诊断。切除残留的色斑痣也发现了大汗腺囊腺瘤，基底细胞样卵泡增生，和皮球瘤。此外，在评估患者皮脂腺痣内的继发性肿瘤时，选择合适的活检部位和大小是很重要的。的确,如果怀疑有额外的诊断,可能需要一次以上的活检.
