关键词: allergens consumer product safety dimethylglyoxime test nickel allergy nickel exposure nickel release nickel screening test

Mesh : Brazil Consumer Product Safety Dermatitis, Allergic Contact / etiology Household Articles Humans Nickel / adverse effects analysis Numismatics Oximes

来  源:   DOI:10.1111/cod.13534   PDF(Sci-hub)

Abstract:
BACKGROUND: Nickel is a ubiquitous element used in many everyday items. In recent decades nickel has become a leading allergen, which has become a public health problem.
OBJECTIVE: To evaluate frequently used nickel products in Brazil. We investigated if these objects release nickel that is capable of inducing sensitization or cause clinical manifestations in terms of allergic contact dermatitis (ACD).
METHODS: Dimethylglyoxime (DMG) spot tests assessed nickel release from several common utensils used in everyday life in São Paulo and Rio de Janeiro, Brazil.
RESULTS: We tested 46 coins (two denominations) and 90 common utensils. Approximately 91.1% produced nickel-positive results using the DMG spot test.
CONCLUSIONS: The DMG limit of detection was 1.67 ppm of nickel. We observed that many objects in our test series released nickel above the DMG test limit. This observation suggests that nickel-sensitive individuals may be exposed to nickel, representing a public health issue.
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