Abstract:
This paper reports 2 cases of female carriers of the FMR1 premutation for developing spontaneous coronary artery dissection (SCAD). These women had classical presentations of premutation symptoms, including anxiety, depression, and connective tissue problems, all of which can contribute to SCAD. These cases suggest a possible connection between the fragile X premutation and a predisposition to SCAD.
摘要:
本文报告2例FMR1前突变女性携带者发生自发性冠状动脉夹层(SCAD)。这些女性有典型的突变前症状,包括焦虑,抑郁症,和结缔组织问题,所有这些都可以为SCAD做出贡献。这些情况表明,脆性X前突变与SCAD易感性之间可能存在联系。