PDF(Pubmed)
Abstract：
BACKGROUND: Objectives: The main aim of this study was to compare, by a new automated colorimetric method, oxidant and anti-oxidant status of those who fast during Ramadan and those who do not. For this purpose, total oxidant status (TOS), total anti-oxidant capacity (TAC) levels and oxidative stress index (OSI) were analysed. By doing this, we hope to examine whether fasting has any beneficial effect on human health.
METHODS: Fifty seven people were included in this study. Of these, 30 people had been fasting during the month of Ramadan for at least ten years, but 27 had never fasted in their life. On the 15th day of Ramadan, blood samples were obtained from both groups after 12 hours of fasting.
RESULTS: The TAC levels of the fasting group (1.29±0,19) was quite higher than the non-fasting group (1,09±0,16) [EIC2][ICD3] [ICD4](p< 0.001). Similarly, in the fasting group TOS level and the OSI (respectively 12,77±2,23 and 1,01±0,25) was quite lower [EIC5][ICD6][ICD7] than in the non-fasting group (respectively 14,15±2,04 and 1,33±0,30), (p<=0.019 and p<0.001, respectively).These findings show that the TOS level of non-fasting group was high. This oxidative stress might cause various illnesses. Therefore, fasting could play a significant part in health-protection by increasing total anti-oxidant capacity.
METHODS: Fifty seven people were included in this study. Of these, 30 people had been fasting during the month of Ramadan for at least ten years, but 27 had never fasted in their life. On the 15th day of Ramadan, blood samples were obtained from both groups after 12 hours of fasting.
RESULTS: The TAC levels of the fasting group (1.29±0,19) was quite higher than the non-fasting group (1,09±0,16) [EIC2][ICD3] [ICD4](p< 0.001). Similarly, in the fasting group TOS level and the OSI (respectively 12,77±2,23 and 1,01±0,25) was quite lower [EIC5][ICD6][ICD7] than in the non-fasting group (respectively 14,15±2,04 and 1,33±0,30), (p<=0.019 and p<0.001, respectively).These findings show that the TOS level of non-fasting group was high. This oxidative stress might cause various illnesses. Therefore, fasting could play a significant part in health-protection by increasing total anti-oxidant capacity.
摘要：
背景：目的：本研究的主要目的是比较，通过一种新的自动比色法，斋月期间禁食和不禁食的人的氧化剂和抗氧化剂状态。为此,总氧化剂状态（TOS），分析总抗氧化能力（TAC）水平和氧化应激指数（OSI）。通过这样做，我们希望研究禁食是否对人类健康有任何有益影响。
方法：本研究纳入57人。其中,30人在斋月期间禁食至少十年，但是27人一生中从未禁食。在斋月的第15天，两组均在禁食12小时后采集血样.
结果：空腹组的TAC水平（1.29±0,19）明显高于非空腹组（1,09±0,16）[EIC2][ICD3][ICD4]（p<0.001）。同样，在空腹组的TOS水平和OSI（分别为12,77±2,23和1,01±0,25）[EIC5][ICD6][ICD7]比非空腹组（分别为14,15±2,04和1,33±0,30），(分别为p<=0.019和p<0.001)。这些发现表明非禁食组的TOS水平较高。这种氧化应激可能导致各种疾病。因此,禁食可以通过增加总抗氧化能力在健康保护中发挥重要作用。
方法：本研究纳入57人。其中,30人在斋月期间禁食至少十年，但是27人一生中从未禁食。在斋月的第15天，两组均在禁食12小时后采集血样.
结果：空腹组的TAC水平（1.29±0,19）明显高于非空腹组（1,09±0,16）[EIC2][ICD3][ICD4]（p<0.001）。同样，在空腹组的TOS水平和OSI（分别为12,77±2,23和1,01±0,25）[EIC5][ICD6][ICD7]比非空腹组（分别为14,15±2,04和1,33±0,30），(分别为p<=0.019和p<0.001)。这些发现表明非禁食组的TOS水平较高。这种氧化应激可能导致各种疾病。因此,禁食可以通过增加总抗氧化能力在健康保护中发挥重要作用。
