关键词: Multiple myeloma, Paraprotein, Immunoglobulin

Mesh : Adult Age Factors Aged Aged, 80 and over Cross-Sectional Studies Female Humans Immunoglobulin A / metabolism Immunoglobulin G / metabolism Immunoglobulin kappa-Chains / metabolism Immunoglobulin lambda-Chains / metabolism Male Middle Aged Multiple Myeloma / metabolism Paraproteins / metabolism Sex Factors

来  源:   DOI:10.5455/JPMA.21075

Abstract:
OBJECTIVE: To determine the types of paraproteins in patients with multiple myeloma in a tertiary care setting.
METHODS: The cross-sectional study was conducted at the Liaquat National Hospital, Karachi, from November 2015 to May 2016, and comprised patients with multiple myeloma selected using consecutive, non-probability sampling technique. Detailed history was taken and immunofixation assay was conducted to assess the type of paraproteins in the patients. Data was recorded on a proforma and analysed using SPSS 22.
RESULTS: Of the 87 patients, 62(71.3%) were males and 25(28.7%) were females. The overall mean age was 57.41±10.53 years. Of the total, 52(71.3%), patients had Immunoglobulin G kappa and 61(70%) had Immunoglobulin A kappa paraprotein.
CONCLUSIONS: The most common types of paraprotein was found to be Immunoglobulin G kappa followed by Immunoglobulin A kappa.
摘要:
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