AGReMA will be developed over five overlapping stages. Stage one will comprise a systematic review to examine relevant evidence on the quality of reporting in published studies that use mediation analysis. In the second stage we will consult a group of methodologists and applied researchers by using a Delphi process to identify items that should be considered for inclusion in AGReMA. The third stage will involve a consensus meeting to consolidate and prioritise key items to be included in AGReMA. The fourth stage will involve the production of AGReMA and an accompanying explanation and elaboration document. In the final stage we will disseminate the AGReMA statement via journals, conferences, and professional meetings across multiple disciplines.
The development and implementation of AGReMA will improve the standardization, transparency, and completeness in the reporting of studies that use mediation analysis to understand the mechanisms of health interventions and exposures.
AGReMA将分为五个重叠阶段进行开发。第一阶段将包括系统审查,以检查使用调解分析的已发表研究报告质量的相关证据。在第二阶段,我们将使用Delphi过程咨询一组方法学家和应用研究人员,以确定应考虑纳入AGReMA的项目。第三阶段将涉及一次共识会议,以合并和优先考虑将包括在AGReMA中的关键项目。第四阶段将涉及制作AGReMA以及随附的解释和详细说明文件。在最后阶段,我们将通过期刊传播AGReMA声明,会议,和跨多个学科的专业会议。
AGReMA的开发和实施将提高标准化,透明度,以及使用中介分析来了解健康干预和暴露机制的研究报告的完整性。