关键词: ALK Drug delivery system Gold nanoparticle Multi-headed PROTAC Target protein degradation
Mesh : Anaplastic Lymphoma Kinase / antagonists & inhibitors chemistry metabolism Antineoplastic Agents / chemical synthesis chemistry pharmacology Cell Proliferation / drug effects Cell Survival / drug effects Drug Delivery Systems Drug Screening Assays, Antitumor Gold / chemistry metabolism Humans Metal Nanoparticles / chemistry Molecular Structure Particle Size Protein Kinase Inhibitors / chemical synthesis chemistry pharmacology Proteolysis Surface Properties Thalidomide / analogs & derivatives chemical synthesis chemistry pharmacology Tumor Cells, Cultured
来 源:
DOI:10.1016/j.colsurfb.2020.110795
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