blinatumomab 在日本成人复发性 / 难治性急性淋巴细胞白血病中的 1b / 2 期研究。
关键词: Japan acute lymphoblastic leukemia blinatumomab clinical study phase 1b refractory relapsed
Mesh : Adult Aged Antibodies, Bispecific / administration & dosage adverse effects blood pharmacokinetics Antigens, CD19 / genetics immunology B-Lymphocytes / pathology CD3 Complex / genetics immunology Dexamethasone / administration & dosage Disease-Free Survival Dose-Response Relationship, Drug Female Humans Interferon-gamma / blood Kaplan-Meier Estimate Lymphoma, B-Cell / blood drug therapy pathology Male Middle Aged Neoplasm, Residual / blood drug therapy pathology Precursor Cell Lymphoblastic Leukemia-Lymphoma / blood drug therapy pathology Remission Induction T-Lymphocytes / immunology
来 源:
DOI:10.1111/cas.14322
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