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Abstract：
Cloacal dysgenesis sequence occurs as a result of complete developmental failure of the urorectal septum. Typically, the sequence is featured by a smooth perineum, without any urethral, genital or anal openings. Its clinical manifestation differs throughout gestation. We report an interesting case of first trimester megacystis with associated umbilical cord abnormalities in a female fetus having cloacal dysgenesis sequence. This rare association reflecting high urinary pressure should first suggest urethral atresia. Our case highlights the importance of routine inspection of umbilical cord in the workup of early megacystis in terms of both etiology and fetal diagnosis.
摘要：
泄殖腔发育不全序列是由于尿道直肠间隔完全发育失败而发生的。通常,序列的特点是平滑的会阴，没有任何尿道，生殖器或肛门开口。其临床表现在整个妊娠期间不同。我们报告了一个有趣的案例，即在具有泄殖腔发育不全序列的女性胎儿中，妊娠早期巨细胞与脐带异常相关。这种罕见的反映高尿压的关联应该首先提示尿道闭锁。我们的案例强调了在病因和胎儿诊断方面，脐带常规检查在早期巨细胞检查中的重要性。
