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Abstract：
This review provides a summary of recent research on biomimetic and bioinspired strategies applied in the field of biomedical material engineering and focusing particularly on calcium phosphate-protein template constructs inspired by biomineralisation. A description of and discussion on the biomineralisation process is followed by a general summary of the application of the biomimetic and bioinspired strategies in the fields of biomedical material engineering and regenerative medicine. Particular attention is devoted to the description of individual peptides and proteins that serve as templates for the biomimetic mineralisation of calcium phosphate. Moreover, the review also presents a description of smart devices including delivery systems and constructs with specific functions. The paper concludes with a summary of and discussion on potential future developments in this field.
摘要：
这篇综述总结了最近在生物医学材料工程领域应用的仿生和生物启发策略的研究，特别关注受生物矿化启发的磷酸钙-蛋白质模板构建体。对生物矿化过程的描述和讨论之后，对仿生和生物启发策略在生物医学材料工程和再生医学领域的应用进行了概述。特别注意用作磷酸钙仿生矿化模板的单个肽和蛋白质的描述。此外，审查还介绍了智能设备，包括具有特定功能的交付系统和结构。本文最后总结并讨论了该领域的潜在未来发展。
