Fe (II) / α - 酮戊二酸双加氧酶 AlkB 催化 DNA 去甲基化的单周转动力学研究.
关键词: DNA demethylation FRET analysis conformational dynamics dioxygenase AlkB fluorescent probes protein–DNA interactions single-turnover kinetics stopped-flow method
Mesh : Catalysis DNA / chemistry metabolism DNA Demethylation DNA, Single-Stranded / chemistry metabolism Escherichia coli / enzymology Escherichia coli Proteins / chemistry metabolism Fluorescent Dyes / chemistry Kinetics Mixed Function Oxygenases / chemistry metabolism Models, Molecular Oligonucleotides / chemistry metabolism Protein Conformation
来 源:
DOI:10.3390/molecules24244576
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