Mesh : Animals Disease Models, Animal Humans Mice Nociceptors / physiology Pain / physiopathology Pain Measurement / methods Rats

来  源:   DOI:10.30802/AALAS-CM-19-000062   PDF(Sci-hub)   PDF(Pubmed)

Abstract:
Pain is a clinical syndrome arising from a variety of etiologies in a heterogeneous population, which makes successfully treating the individual patient difficult. Organizations and governments recognize the need for tailored and specific therapies, which drives pain research. This review summarizes the different types of pain assessments currently being used and the various rodent models that have been developed to recapitulate the human pain condition.
摘要:
疼痛是由异质性人群中的多种病因引起的临床综合征,这使得成功治疗个体患者变得困难。组织和政府认识到需要量身定制的特定疗法,推动疼痛研究。这篇综述总结了目前正在使用的不同类型的疼痛评估以及为概述人类疼痛状况而开发的各种啮齿动物模型。
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