Abstract：
BACKGROUND: This Dutch travel Vaccination Study (DiVeST) aimed to study adherence or compliance to Dutch travel health guidelines in travelling families and to identify risk groups to provide better advice and protection for international travellers.
METHODS: Between 2016 and 2018, family members who travelled to Eastern Europe or outside Europe during the preceding year were recruited via Dutch secondary schools. The vaccination status of the travellers was assessed using questionnaires and vaccination records and hepatitis A virus antibody concentrations in dried blood spot (DBS) eluates. Subgroups of travellers with lower adherence to guidelines were identified.
RESULTS: Of the 246 travellers that participated in this study, 155 (63%) travelled to destinations for which the HAV vaccination was recommended. Of these 155 travellers, 56 (36%) said they visited a pre-travel clinic, and 64 of them (41%) showed a valid HAV vaccination in their vaccination records. Of the 145 travellers with available DBS eluates, anti-HAV antibodies were detected in 98 (68%) of them.
CONCLUSIONS: We found that adherence to travel health guidelines, in terms of HAV vaccination, was suboptimal. According to our results, specific attention should be paid to children, persons visiting friends and relatives and those who travel relatively short distances.
METHODS: Between 2016 and 2018, family members who travelled to Eastern Europe or outside Europe during the preceding year were recruited via Dutch secondary schools. The vaccination status of the travellers was assessed using questionnaires and vaccination records and hepatitis A virus antibody concentrations in dried blood spot (DBS) eluates. Subgroups of travellers with lower adherence to guidelines were identified.
RESULTS: Of the 246 travellers that participated in this study, 155 (63%) travelled to destinations for which the HAV vaccination was recommended. Of these 155 travellers, 56 (36%) said they visited a pre-travel clinic, and 64 of them (41%) showed a valid HAV vaccination in their vaccination records. Of the 145 travellers with available DBS eluates, anti-HAV antibodies were detected in 98 (68%) of them.
CONCLUSIONS: We found that adherence to travel health guidelines, in terms of HAV vaccination, was suboptimal. According to our results, specific attention should be paid to children, persons visiting friends and relatives and those who travel relatively short distances.
摘要：
背景：这项荷兰旅行疫苗接种研究（DiVeST）旨在研究旅行家庭对荷兰旅行健康指南的依从性或依从性，并确定风险人群，为国际旅行者提供更好的建议和保护。
方法：在2016年至2018年之间，前一年前往东欧或欧洲以外地区的家庭成员通过荷兰中学招募。使用问卷调查和疫苗接种记录以及干血斑（DBS）洗脱液中的甲型肝炎病毒抗体浓度评估旅行者的疫苗接种状态。确定了对指南依从性较低的旅行者亚组。
结果：在参与本研究的246名旅行者中，155人（63%）前往建议接种HAV疫苗的目的地。在这155名旅客中，56（36％）表示他们参观了旅行前诊所，其中64人(41%)在疫苗接种记录中显示有效的HAV疫苗接种。在145名旅客中，有可用的星展银行洗脱液，其中98例(68%)检测到抗HAV抗体.
结论：我们发现，遵守旅行健康指南，在HAV疫苗接种方面，是次优的。根据我们的结果,应该特别注意儿童，拜访朋友和亲戚的人以及旅行距离相对较短的人。
方法：在2016年至2018年之间，前一年前往东欧或欧洲以外地区的家庭成员通过荷兰中学招募。使用问卷调查和疫苗接种记录以及干血斑（DBS）洗脱液中的甲型肝炎病毒抗体浓度评估旅行者的疫苗接种状态。确定了对指南依从性较低的旅行者亚组。
结果：在参与本研究的246名旅行者中，155人（63%）前往建议接种HAV疫苗的目的地。在这155名旅客中，56（36％）表示他们参观了旅行前诊所，其中64人(41%)在疫苗接种记录中显示有效的HAV疫苗接种。在145名旅客中，有可用的星展银行洗脱液，其中98例(68%)检测到抗HAV抗体.
结论：我们发现，遵守旅行健康指南，在HAV疫苗接种方面，是次优的。根据我们的结果,应该特别注意儿童，拜访朋友和亲戚的人以及旅行距离相对较短的人。
